What Is The Treatment for Cyst Hemorrhage In PKD Patients
In our country, there are about 1.5 million patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) and the global incidence is about 1‰-2‰, which is the fourth leading cause of renal replacement therapy. And cyst hemorrhage is also a common complication of ADPKD.
Clinical manifestations of PKD
ADPKD is a common hereditary renal disease characterized by progressive enlargement of renal cysts. The incidence is about 1 in 400-1000 live births. However, ADPKD usually has insidious clinical symptoms and low diagnostic rate. Although the mechanism of ADPKD cyst formation is still unclear, it is known to be caused by functional defects of polycystic protein 1 or polycystic protein 2. ADPKD clinical manifestations are various and the common symptoms include: pain, high blood pressure, hematuria, urinary tract infection, stone or calcium. Besides, ADPKD also has many extrarenal manifestations like liver cyst, cystis vesiculae seminalis, abnormalities of connective tissue, laparacele, pancreatic cyst, intracranial aneurysm and meningeal cysts.
What is the treatment for cyst hemorrhage?
Renal cyst hemorrhage is a common complication of ADPKD, with an incidence of up to 70%.
The main clinical manifestations are low back pain with tenderness and/or hematuria. Low back pain is mainly caused by cyst hemorrhage and renal capsule tension, while hematuria is caused by cyst rupture and blood into the collection system.
Spontaneous and non-fatal hemorrhage of retroperitoneal cysts is rare in this case. According to studies, only 3% of patients with ADPKD have perinephric hematoma.
The treatment of cyst bleeding is mainly conservative treatment, such as bed rest to relieve pain, intravenous infusion, analgesia (non-steroidal anti-inflammatory drugs should not be used). Most hematuria is self-limited and usually lasts 2-7 days. But too much bleeding and blood clots may lead to urinary tract obstruction. Ureteral stenting is required if the obstruction persists for more than 2 weeks. Patients with severe bleeding due to extensive subcapsular or retroperitoneal hematoma should be treated with blood transfusion or transcatheter arterial embolization.
More importantly, the key treatment for PKD is to shrink kidney cysts and stop their growth. In this way, kidney cysts will not burst and cause bleeding. If you want to know more information, you can leave a message below or consult our online doctor directly.
***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***