Top 5 Common Complications of Nephrotic Syndrome

Nephrotic Syndrome, ComplicationsNephrotic Syndrome is not an independent disease, but a group of symptoms. Without timely treatment, it can cause a lot of complications. Here are the top 5 common complications of Nephrotic Syndrome.

(1) Infection

Because a large number of immunoglobulins are lost from the urine, plasma protein is reduced, affecting the formation of antibodies. The application of adrenocortical hormones and cytotoxic drugs makes the patient's systemic resistance decrease, and it is easy to cause infection, such as skin infection, primary peritonitis, respiratory tract infection, urinary tract infection, and even induce sepsis.

(2) Coronary heart disease

Patients with Nephrotic Syndrome often have hyperlipidemia and hypercoagulability, so they are prone to coronary heart disease. It has been reported that the incidence of myocardial infarction in patients with nephrotic syndrome is eight times higher than that in normal people. Coronary heart disease has become the third cause of death in nephrotic syndrome (after infection and Kidney Failure).

(3) Thrombosis

Nephrotic syndrome patients are prone to thrombosis, especially membranous nephropathy incidence can reach 25%-40%. The causes of thrombosis include edema, less activity of patients, venous stasis, hyperlipidemia, increased blood viscosity due to blood concentration, excessive fibrinogen content, increased factors of v, ⅶ, ⅷ, and x, and the use of adrenocortical hormones, which make blood prone to hypercoagulability.

(4) Acute renal failure

Nephrotic syndrome patients are often in a state of low blood volume and high coagulation due to massive proteinuria, hypoproteinemia and hyperlipidemia. When vomiting, diarrhea, antihypertensive drugs and diuretics are used in a large amount of diuresis, the blood perfusion volume of the kidney can be dramatically reduced, thereby reducing the glomerular filtration rate, leading to acute renal failure. In addition, renal interstitial edema in nephrotic syndrome, tubular blockage of protein concentration and other factors can also induce acute renal failure.

(5) Electrolyte and metabolic disorders

Repeated use of diuretics or long-term unreasonable prohibition of salt can make patients with nephrotic syndrome secondary to hyponatremia; the use of adrenocortical hormones and a large number of diuretics lead to a large number of urination, if not timely potassium supplementation, prone to hypokalemia.

Now you know the top 5 common complications of Nephrotic Syndrome. Hope you take treatment as early as possible to control Nephrotic Syndrome well so as to prevent the occurrence of those complications. If you are not satisfied with current steroid treatment and immunosuppressants, you can try systemic Chinese Medicine Treatment, which can help you have a permanent control of the disease. For more information on Nephrotic Syndrome treatment, please leave a message below or contact online doctor.


***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***

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