How to Deal with Repeated Hematuria for IgA Nephropathy Patients

How to Deal with Repeated Hematuria for IgA Nephropathy PatientsHematuria is a typical symptom of IgA Nephropathy (Berger’s Disease). whenever you have infections such as catching a cold, it is prone to blood urine. How to deal with repeated hematuria for IgA Nephropathy patients? Read on to learn more information.

Manifestations of hematuria in different stages of IgA Nephropathy

IgA nephropathy can be divided into five stages according to the course of nephrological changes:

IgA Nephropathy stage 1

There is no abnormality except for a slight broadening of the mesangium.

Only intermittent urine occult blood is present, usually undetected.

IgA Nephropathy stage 2

The mesangial area begins to show focal proliferation and hardening, but there are no other abnormalities.

At this time, there is still only intermittent urine occult blood, but this is a little bit more frequent than the first stage. And it is still difficult to detect.

IgA Nephropathy stage 3

The proliferation and broadening of the mesangial area begin to be diffuse, and the glomeruli begin to form crescents, while the tubules and interstitium begin to form focal edema and cell infiltration.

This stage is a watershed. Urine occult blood begins to appear continuously, and a few patients can also appear proteinuria, high blood pressure and some other symptoms. Most cases are diagnosed in this stage.

IgA Nephropathy stage 4

Mesangial hyperplasia and sclerosis have become severely diffuse, glomerulosclerosis has begun to appear, and tubular atrophy and interstitial infiltration are also worse. The glomerular crescent has reached nearly 50%, and renal damage has become severe.

In this stage, renal insufficiency has already appeared. In addition to urine occult blood, urinary protein, hypertension and other symptoms are also relatively serious, and the effects of renal insufficiency begin to appear, such as anemia, electrolyte disorder, bone disease, heart failure and so on.

IgA Nephropathy stage 5

Stage 5 is similar to stage 4, but more severe. The glomerular crescent is more than 50% and is progressing toward end stage.

This stage is the most difficult to treat, because renal function has been seriously reduced, and some patients have reached the stage of uremia, so conservative treatment is mainly used.

Difficulty in the treatment of IgA Nephropathy

The difficulty in the treatment of IgA nephropathy is not only that the IgA immune complex deposited in the mesangial area is difficult to clean up, but also that proliferation and sclerosis in the mesangial area will lead to a large amount of glomerular sclerosis and necrosis.

What's more, it also leads to atrophy and infiltration of renal tubules and interstitium, resulting in a sharp decline in renal function. About 10% to 20% of patients will enter the stage of chronic renal failure within 10 years.

IgA nephropathy is still mainly treated by routine therapy, namely the treatment for symptoms such as urinary occult blood, urinary protein and hypertension.

The therapeutic effect is poor and mainly depends on the compensatory function of residual nephron.

New treatment of IgA Nephropathy

In addition to western medicine symptomatic treatment, you can try Chinese medicine.

Chinese medicine treatment of IgA nephropathy is mainly to alleviate renal cell sclerosis.

We know that both glomerular sclerosis and tubular atrophy have a significant impact on renal function, and this sclerosis is irreversible. If the rate of sclerosis can be slowed, the rate of progression of IgA nephropathy will be greatly reduced.

The Traditional Chinese Medicine method of delaying renal cell sclerosis is to solve the state of renal cell ischemia and hypoxia by improving renal microcirculation.

Because both the deposition of IgA and the proliferation of mesangium will lead to the obstruction of renal microcirculation. For the kidney itself, a capillary group, it will lead to a large number of renal cells in the state of ischemia and hypoxia, which is the main reason for sclerosis and atrophy.

Therefore, to achieve better result, you can use traditional Chinese medicine to improve the kidney microcirculation, and combine with western medicine symptomatic treatment. When kidney function gets improved, repeated hematuria will vanish completely.

How to deal with repeated hematuria for IgA Nephropathy patients? Now you get the answer. If you would like to know more information on IgA Nephropathy, please leave a message below or contact online doctor.


***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***

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