Why Is It Important to Control Blood Sugar Level for Patients with Diabetic Nephropathy

Why Is It Important to Control Blood Sugar Level for Patients with Diabetic NephropathyWhat problems should be paid attention to in the treatment of Diabetic Nephropathy (DN)? why is it important to control blood sugar? In this article, let’s have a quick look.

For DN treatment, attention should be paid to the three aspects: blood glucose control, blood pressure control and blood lipid regulation, among which effective blood glucose control is the most important measure to delay the disease progression of DN patients. The reasons are as follows:

Hyperglycemia is an important and independent risk factor for the progression of all types of diabetes to DN to ESRD. Good blood glucose control can delay the progression of diabetic kidney disease (DKD). Therefore, blood glucose control is particularly important for the protection of diabetic kidney damage. In addition, some other problems should be paid attention in the process of lowering blood glucose.

  1. It is important to use drugs to lower blood glucose, but we should recognize the role of reasonable diet and proper exercise in controlling blood sugar. And we should take lifestyle improvement as the first step to delay the progress of DKD, and consider drug treatment when the improvement is ineffective.
  2. The status of renal function must be considered when using hypoglycemic drugs. Because the kidney is the main organ of drug metabolism, many hypoglycemic drugs are excreted through the kidney. If the patient's kidneys are not functioning properly, the drug is stored in the body, and it may cause hypoglycemia. It should be noted that hypoglycemia is more harmful to the body than hyperglycemia.
  3. Metformin is an old drug. Recently, relevant international guidelines have proposed that metformin can be used as the basic drug for hypoglycemic treatment, whether it is a combination of two or three. However, in clinical treatment with metformin, the renal function of patients should also be considered, and appropriate reduction or discontinuation should be made according to the stage of CKD.

Patients with DKD are often associated with hypertension, which is an important cause of aggravating renal injury and diabetes cardiovascular disease. Therefore, strict control of blood pressure is another key point of treatment. However, when controlling blood pressure, attention should be paid to the target of blood pressure reduction, and different age, proteinuria level and CKD stage should be mastered, so the targets of blood pressure control are different. In addition, the use of single or combined use of antihypertensive drugs is also very important. Currently, ACEI and ARB drugs are still the preferred drugs for the prevention and treatment of DKD hypertension and the reduction of proteinuria. Other diuretics, CCB and aldosterone receptor antagonists can also be selected in combination according to the patient's situation.

In addition, most patients with DKD have abnormal lipid metabolism, such as high cholesterol and triglyceridemia, which are closely related to the progression of DKD. Therefore, the regulation of dyslipidemia should also be emphasized. Other anticoagulant, antiplatelet and vitamin D may also be used as adjuvant therapy.

Now you know controlling blood sugar level is important in the treatment of Diabetic Nephropathy. For more information on Diabetic Nephropathy treatment, please leave a message below or contact online doctor.


***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***

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