Under 4 Conditions, Creatinine Elevation Can Be Reduced

Creatinine Elevation, Reduce CreatinineIncreased serum creatinine is the inevitable result of impaired renal function. It means more and more toxins in the body and worse living environment of the kidney. Failure to remove creatinine in time will increase the risk of uremia.

Some kidney patients and family members become panic when they find creatinine elevation. They are afraid that they will develop uremia and have to start dialysis. In fact, kidney function usually progress very slowly, and creatinine rise will not be too fast. There are many factors that lead to creatinine elevation. To avoid creatinine elevation and accelerate renal failure, Kidney patients should do one thing first - to diagnose the cause.

Under 4 conditions, elevated creatinine can be reduced, and kidney function can even be reversed.

1. Creatinine elevation caused by primary disease

Kidney disease is a complex and diverse disease. Some primary kidney disease such as Chronic Nephritis, Lupus Nephritis, and Nephrotic Syndrome, with the deterioration of renal function, will lead to the increase of creatinine. Generally, creatinine is between 200-300 umol/L. At this time, we should inhibit the inflammation reaction of kidney in time, make good use of steroids and immunosuppressants, control the symptoms of proteinuria and edema, and maintain the stability of renal function. In this way, serum creatinine can be reduced or even recovered.

Some patients feel that their treatment seems to have entered a "bottleneck period". Creatinine is stable at certain level. It does not go up or go down. Creatinine is an index to measure renal function. If it is at a stable level for a long time, it means that renal function is also stable. Kidney patients need not go too far in pursuit of falling to normal value. We should know that the complete reversal of renal function damage is very difficult.

2. Creatinine elevation caused by infections

Kidney patients have low immunity and are more susceptible to infection than normal people, including respiratory tract infections such as colds, oral infections such as periodontitis, urinary infections such as kidney stones and so on. Infection can lead to active inflammation in the body, increase of toxins such as immune complexes, and thus increasing creatinine.

Once the infection is diagnosed, kidney friends can timely identify the source of infection and carry out anti-infective treatment, such as some anti-infective drugs such as ribavirin, acyclovir, and so on. At the same time, adjust diet and exercise to improve immunity. In most cases, creatinine level can fall back, and will not continue to rise.

3. Creatinine elevation caused by fever

Some kidney patients will have fever, sweating, high fever and other conditions in the course of treatment, which will lead to the reduction of water in the body, insufficient blood volume, and blood concentration, leading to increased serum creatinine. Causes of fever, high fever and sweating are colds, inflammation recurrence and so on.

To avoid deterioration of the condition, first of all, we should diagnose the cause of fever. Secondly, after insufficient blood volume, we should avoid blood concentration. Kidney patients can take more water or normal saline and glucose to improve blood flow and reduce renal ischemia so as to maintain the stability of renal function.

4. Creatinine elevation caused by anti-hypertensive drugs

Some drugs have side effects of increasing creatinine, such as ACEI and ARBs, which have the functions of lowering blood pressure, lowering proteinuria and protecting kidney. They are suitable for patients with kidney disease below 265 creatinine. However, it is not suitable for patients with renal insufficiency and renal failure, mainly because they can increase creatinine.

In this case, first of all, the dosage can be adjusted. If the effect is not obvious, alternative drugs can be chosen. Normally, creatinine will drop to the original value and will not cause the disease to deteriorate.

Most of the creatinine elevation caused by these factors can be restored and the renal function will not be damaged, but once the renal function is damaged more than 50%, it is almost impossible to completely restore, so the complete recovery of creatinine is unrealistic. To maintain the stability of creatinine, in the final analysis, we should maintain the stability of renal function, which is the focus of kidney disease treatment.


***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***

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