Three Commonly Used Drugs for Kidney Disease
For patients with impaired renal function, with the progression of renal disease, there will be a variety of symptoms, such as typical proteinuria, hypertension, edema, anemia, high blood potassium, etc.. In order to avoid accelerating Kidney Failure, it is often necessary to take a combination of drugs.
Kidney is an important metabolic organ. Most drugs need to be metabolized through renal filtration. This also makes many kidney patients worry that kidneys exposuring to more drugs will increase the risk of drug-induced kidney damage?
As we all say, almost all drugs have toxicity. If they are used correctly, they can control the disease very well, but if they are used wrongly, they can cause further damage to your health. Today I have sorted out some matters needing attention in the daily so as to help kidney patientsavoidsome mistakes in medication.
Anti-hypertensive drugs: take ACEI or ARBs for an example.
For these two kinds of antihypertensive drugs, kidney patients should not be unfamiliar. They have the function of lowering the level of proteinuria and delaying renal function. They are indispensable drugs for kidney disease treatment. But these two drugs are not suitable for all kidney patients. Generally, they can not be used in kidney patients who have been diagnosed as renal insufficiency and creatinine level is over 265. In addition, patients with bilateral renal artery stenosis, pregnancy, as well as those with hyperkalemia, can not use these two drugs.
It is worth noting that these two drugs have the side effects of ascending creatinine and increasing blood potassium. Therefore, kidney patients taking these two drugs should pay attention to monitoring the levels of blood potassium and creatinine, which is more conducive to maintaining the efficacy and ensuring the stability of renal function.
Lipid-lowering drugs: take statins for an example
Some patients have high blood cholesterol level, so they need to take appropriate lipid-lowering drugs to control blood lipids so as not to aggravate the condition of renal arteriosclerosis. Statins are one of the commonly used lipid-lowering drugs and have been studied to reduce the level of proteinuria.
The study found that lipid-lowering drugs with shorter half-life had better effect in the evening than in the morning, mainly reflected in the reduction of total cholesterol and low density lipoprotein cholesterol. Long half-life lipid-lowering drugs such as atorvastatin had little difference in the morning and evening.
Note: Half-life refers to the time taken to reduce the amount of drugs in the body to one-half, and it is a judgment of the concentration of drugs in the blood.
Steroids and immunosuppressants
Steroid drugs are indispensable for the treatment of kidney disease, but they are also controversial drugs. In addition to obvious side effects, some patients can not achieve a good effect on reducing proteinuria after taking steroids, whichis often related to drug dosage and time.
It is suggested that we start to take steroids in sufficient quantities, slowly reduce the dosage after the improvement of the condition, and maintain the dosage for a long time, which is more conducive to the stability of proteinuria and kidney function. We can not stop abruptly to avoid the recurrence of the disease. Taking steroids in the morning has fewer side effects. For steroid-dependent patients, it can be taken with other antiproteinuria drugs.
Immunosuppressants are usually taken in conjunction with steroids to eliminate inflammation, and the efficacy of some immunosuppressive drugs may be affected by food. If taking tacrolimus, it is best to have an empty stomach, after meal or before meal. If you take this kind of medicine and eat grapefruit at the same time, it will increase the blood concentration of drugs, affect the efficacy of drugs, and is not conducive to the stability of the disease. There are other drugs and foods that are contraindicated, such as after taking cold medicines with antipyretic and analgesic ingredients, you can not drink alcohol. Kidney patients should also pay more attention to this knowledge.
Now you know the three commonly used drugs for kidney disease. For more information on kidney disease treatment, please leave a message below or contact online doctor.
***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***